[Melanoma of the head and neck region in material of Department of Oncological and Reconstructive Surgery in Center of Oncology IMSC in Gliwice].
نویسندگان
چکیده
INTRODUCTION About 25% of melanomas are localized in head and neck skin, and this particular localization is most difficult to treat, and the prognosis is less favorable. The depth of melanoma infiltration (Clark and Breslau grade) into the skin is the main factor of local advancement of the disease. Surgical treatment is an essential therapeutic modality in patients with melanoma. AIM The aim of this study was to evaluate results of our surgical treatment of melanomas in head and neck localisation, treated from 1997 to 2007 in Department of Oncological and Reconstructive Surgery in Center of Oncology IMSC in Gliwice. MATERIAL We analysed group of 47 patients (aged 26 to 75 years, mean 49), treated by surgical excision of malignant melanoma in the head and neck region. Most of the patiens required to use free flaps or skin graft technique to close posexcisional defect, on basis of clinical considerations. RESULTS The 5-year total survival for all patients was 62% and were dependent on depht of melanoma infiltration and regional lymph node metastasis. The significant prognostic factors were: localization of primary focus, local progression of disease, free microscopical excision margins sex and age. CONCLUSIONS Prognosis in the patients with melanoma of the head and neck is unreliable and dependent on local advancement of disease and localization of primary focus. Surgical treatment is an essential therapeutic modality in patients with melanoma. Adiuvant radiotherapy after surgical treatment of melanoma of the head and neck is intended for the patiens with high risk of local or regional recurence of disease.
منابع مشابه
Chondroradionecrosis of the Larynx in a Patient with Laryngeal: A Case Report
Introduction: Actinomycosis of the larynx has been rarely reported in the literature and usually occurs in patients with a history of laryngeal carcinoma and radiation therapy. However, its co-existence with chondroradionecrosis due to radiotherapy is even rarer. The most common site of infection is the cervicofacial region, especially in the submandibular area. Case Report: Here we report a ...
متن کاملMalignant Melanoma of the External Auditory Canal:A Rare Entity
Introduction: Although malignant melanomas (MM) are common in the head and neck region; primary malignant melanoma of the external auditory canal (EAC) is rare. Case Report: We present the case of a 50-year-old symptomatic man with a malignant melanoma of the external auditory canal, which clinically masqueraded as a haemangioma. The patient subsequently developed extensive loco-regional me...
متن کاملEpidemiological aspects of head and neck cancers in a population of south east region of Iran
Introduction: The geographical distribution of head and neck cancer shows considerable variation and it is site dependent. The review of the literature shows few data concerning the head and neck cancer patterns in Iran. The purpose of this study was to represent epidemiological aspects of head and neck cancers in south east of Iran. Materials &Methods: In this retrospective study, from a to...
متن کاملPositional changes in parotid glands during head and neck radiation therapy
Introduction: Xerostomia is the most common complication due to radiation–induced damage to salivary glands in head and neck cancer radiotherapy and it reduces quality of life. Parotid glands are main glands which they are account for secretion of stimulated saliva. Studies have demonstrated that mean tolerance parotid’s radiation dose under 26-30 Gy result in an increase in t...
متن کاملSentinel lymph node biopsy in melanoma patients: An experience with Tc-99m antimony sulfide colloid
Introduction: Sentinel lymph node biopsy is the standard procedure for lymph node staging in intermediate thickness melanoma. In Iran, this procedure has not been addressed sufficiently. In this study, we report our experience in this area. Methods: Ten consecutive patients with intermediate thickness melanoma where included in our study. 1.5 mCi of Tc-99m antimony...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Otolaryngologia polska = The Polish otolaryngology
دوره 64 7 شماره
صفحات -
تاریخ انتشار 2010